Tardive dyskinesia (TD) is a disorder that causes abnormal movements of the body that you cannot control (involuntary movements). TD is often caused by long-term use of dopamine antagonists such as antipsychotics, which are used to treat schizophrenia and other mental health disorders, and certain gastrointestinal agents. These medications may create abnormal dopamine signaling in the brain, which is associated with TD. Dopamine is a chemical in the brain involved in controlling movement. Certain drugs are more likely to cause TD than others. Not everyone who takes antipsychotics will experience TD.